Publikationen unter Nutzung von Material der Biobank

 

2019

Amoury M., Bauerschlag D., Zeppernick F., Von Felbert V., Berges N., Di Diore S., Mintert I., Bleilevens A., Maass N., Bräutigam K., Meinhold-Heerlein I., Stickeler E., Barth S., Fischer R., Hussain A. F.
Photoimmunotheranostic agents for triple-negative breast cancer diagnosis and therapy that can be activated on demand. Oncotarget, Juli 2019, DOI: 10.18632/oncotarget.10705.

Weiskirchen S., Kim P., Weiskirchen R.
Laser Ablation Inductively Coupled Plasma Spectrometry: Metal Imaging in Experimental and Clinical Wilson Disease. Inorganics, April 2019 DOI: 10.3390/inorganics7040054.

Naarmann-de Vries I. S., Sachmann Y., Klein F., Ostareck-Lederer A., Ostareck D. H., Jost E., Ehninger G., Brümmerdorf T. H., Marx G., Röllig C., Thiede C., Crysandt M.
Characterization of acute myeloid leukemia with del(9q) – Impact of the genes in the minimally deleted region. Leukemia Research, Januar 2019 DOI: 10.1016/j.leukres.2018.11.007.

2018

Schulz H., Tator M., Spillner J., Dreher M., Knüchel-Clarke R., Kloten V., Dahl E.
Liquid Biopsy im nicht-kleinzelligen Lungenkarzinom: Die blutbasierte Analyse der ctDNA-Methylierung. Der Pathologe, Oktober 2018 DOI: 10.1007/s00292-018-0536-5.

Langhof, H., Kahrass, H., Illig, T., Jahns, R., & Strech, D.
Current practices for access, compensation, and prioritization in biobanks. Results from an interview study. European Journal of Human Genetics, August 2018 DOI:10.1038/s41431-018-0228-x.

Haase, C., Lethaus, B., Knüchel-Clarke, R., Hölzle F., Cassataro A. Braunschweig T.
Development of a Rapid Analysis Method for Bone Resection Margins for Oral Squamous Cell Carcinoma by Immunoblotting. Head and Neck Pathology, Juni 2018 DOI: 10.1007/s12105-017-0856-4.

Koschmieder S., Brümmendorf T. H.
Biobankinganforderungen aus Sicht des Klinikers. Erfahrungen aus der Hämatologie und Onkologie. Der Pathologe, April 2018, DOI 10.1007/s00292-018-0434-x.

Schlensog M, Magnus L, Heide T, Eschenbruch J, Steib F, Tator M, Kloten V, Rose M, Noetzel E, Gaisa NT, Knüchel R, Dahl E.
Epigenetic loss of putative tumor suppressor SFRP3 correlates with poor prognosis of lung adenocarcinoma patients. Epigenetics April 2018; DOI: 10.1080/15592294.2016.1229730.

Mijnes J., Veeck J., Gaisa N. T., Burghardt E., De Ruijter T. C., Gostek S., Dahl E., Pfister D., Schmid S. C., Knüchel R., Rose M.
Promoter methylation of DNA damage repair (DDR) genes in human tumor entities: RBBP8/CtIP is almost exclusively methylated in bladder cancer. Clinical Epigenetics The official journal of the Clinical Epigenetics Society, Februar 2018, DOI 10.1186/s13148-018-0447-6.

2017

Kloten V, Rüchel N, Ortiz-Brüchle N, Gasthaus J, Freudenmacher N, Steib F, Mijnes J, Eschenbruch J, Binnebösel M, Knüchel R, Dahl E.
Liquid biopsy in colon cancer: comparison of different circulating DNA extraction systems following absolute quantification of KRAS mutations using Intplex allele-specific PCR. Oncotarget. 2017 Sep 21;8(49):86253-86263. doi: 10.18632.

Rose M., Meurer S. K., Kloten V., Weiskirchen R., Denecke B., Antonopoulos W., Deckert M., Knüchel R., Dahl E.
ITIH5 induces a shift in TGF‐β superfamily signaling involving Endoglin and reduces risk for breast cancer metastasis and tumor death. Molecular Carcinogenesis, September 2017, DOI: 10.1002/mc.22742.

Woitok M, Klose D, Di Fiore S, Richter W, Stein C, Gresch G, et al.
Comparison of a mouse and a novel human scFv-SNAP-auristatin F drug conjugate with potent activity against EGFR-overexpressing human solid tumor cells. Onco Targets Ther. 2017 Jul 6;10:3313-3327.

Lebherz C., Schlieper G., Möllmann J., Kahles F., Schwarz M., Bünsing J., Dimkovic N., Koch A., Trautwein C., Flöge J., Marx N., Tacke F., Lehrke M.
GLP-1 Levels Predict Mortality in Patients with Critical Illness as Well as End-Stage Renal Disease. The American Journal of Medicine, Juli 2017 DOI: 10.1016/j.amjmed.2017.03.010.

Garczyk S, Klotz N, Szczepanski S, Denecke B, Antonopoulos W, von Stillfried S, Knüchel R, Rose M, Dahl E.
Oncogenic features of neuromedin U in breast cancer are associated with NMUR2 expression involving crosstalk with members of the WNT signaling pathway. Oncotarget. 2017 May 30;8(22):36246-36265. doi: 10.18632/oncotarget.16121.

2016

Martin L., Horst K., Chiazza F., Oggero S., Collino M., Brandenburg K., Hildebrand F., Marx G., Thiemermann C., Schuerholz T.
The synthetic antimicrobial peptide 19-2.5 attenuates septic cardiomyopathy and prevents down-regulation of SERCA2 in polymicrobial sepsis. Scientific Reports, November 2016 DOI: 10.1038/srep37277 (2016).

Martin L., Peters C., Heinbockel L., Moellmann J., Martincuks A., Brandenburg K., Schuerholz T
The synthetic antimicrobial peptide 19-2.5 attenuates mitochondrial dysfunction in cardiomyocytes stimulated with human sepsis serum. Innate Immunity, September 2016 DOI: 10.1177/1753425916667474.

Lorsy E., Topuz A. S., Geisler C., Stahl S., Garczyk S., Von Stillfried S., Hoss M., Gluz O., Hartmann A., Knüchel R. Dahl E.
Loss of Dickkopf 3 Promotes the Tumorigenesis of Basal Breast Cancer. PLoS One, Juli 2016, DOI: 10.1371/journal.pone.0160077.

Kloten V., Schlensog M.,Eschenbruch J., Gasthaus J., Tiedemann J., Mijnes J., Heide T., Braunschweig T., Knüchel R., Dahl E.
Abundant NDRG2 Expression Is Associated with Aggressiveness and Unfavorable Patients’ Outcome in Basal-Like Breast Cancer. PLoS One, Juli 2016, DOI: 10.1371/journal.pone.0159073.

Dau C., Fliegauf M., Heymut O., Schlensog M., Dahl E., Von Roeyen C. R., Kriz W., Moeller M. J., Braun G. S.
The atypical cadherin Dachsous1 localizes to the base of the ciliary apparatus in airway epithelia. Biochemical and Biophysical Research Communications, Mai 2016, DOI: 10.1016/j.bbrc.2016.04.036.

Schubert C., Allhoff M., Tillmann S., Maié T., Costa I. G., Lipka D. B., Schemionek M., Feldberg K., Baumeister J., Brümmendorf T. H., Chatain N., Koschmieder S.
Differential roles of STAT1 and STAT2 in the sensitivity of JAK2V617F- vs. BCR-ABL-positive cells to interferon alpha. Journal of Hematology & Oncology, April 2016 DOI: 10.1186/s13045-019-0722-9.

Dahl E.
Diagnostik: Liquid Biopsy – Status 2016. Deutsches Ärzteblatt 2016; 113(39): [4]; DOI: 10.3238/PersOnko/2016.09.30.01.
Martin L., Koczera R., Simons N., Zechendorf E., Hoeger J., Marx G., Schuerholz T.
The Human Host Defense Ribonucleases 1, 3 and 7 Are Elevated in Patients with Sepsis after Major Surgery—A Pilot Study. International Journal of Molecular Sciences, Februar 2016 DOI: 10.3390/ijms17030294.

2015

Martin L., Peters C., Schmitz S., Moellmann J., Martincuks A., Heussen N., Lehrke M., Müller-Newen G., Marx G., Schuerholz T.
Soluble Heparan Sulfate in Serum of Septic Shock Patients Induces Mitochondrial Dysfunction in Murine Cardiomyocytes. Shock: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches, Dezember 2015 DOI: 10.1097/SHK.0000000000000462.

Dahl E., Kloten V.
Liquid-biopsy-Analysen mithilfe zellfreier DNA (cfDNA). Möglichkeiten und Grenzen. Der Pathologe, September 2015, DOI: 10.1007/s00292-015-0078-z.

Dötsch M., M.,Kloten V., Schlensog M., Heide T., Braunschweig T., Veeck J., Petersen I., Knüchel R., Dahl E.
Low expression of ITIH5 in adenocarcinoma of the lung is associated with unfavorable patients' outcome. Epigenetics, August 2015, DOI: 10.1080/15592294.2015.1078049.

Martin L, Schmitz S, De Santis R, Doemming S, Haase H, Hoeger J, Heinbockel L, Brandenburg K, Marx G, Schuerholz T.
Peptide 19-2.5 Inhibits Heparan Sulfate-Triggered Inflammation in Murine Cardiomyocytes Stimulated with Human Sepsis Serum. Mai, PLOS ONE 10(5): e0127584.

Bauerschlag D, Maass N, Leonhardt P, Verburg F. A, Pecks U, Zeppernick F, Morgenroth A, Mottaghy F. M, Tolba R, Meinhold-Heerlein I, Bräutigam K.
Fatty Acid Synthase Overexpression: Target for Therapy and Reversal of Hemoresistance in Ovarian Cancer. Journal of Translational Medicine, Mai 2015 13, 146 - 158.

Garczyk S., Von Stillfried S., Antonopoulos W., Hartmann A., Schrauder M. G., Fasching P. A., Anzeneder T., Tannapfel A., Ergönenc Y., Knüchel R., Rose M., Dahl E.
AGR3 in Breast Cancer: Prognostic Impact and Suitable Serum-Based Biomarker for Early Cancer Detection. PloS One, April 2015 DOI: 10.1371/journal.pone.0122106.

Huth S, Heise R, Vetter-Kauczok C. S, Skazik C, Marquardt Y, Czaja K, Knüchel-Clarke R, Merk H. F, Dahl E, Baron J. M.
Inter-a-trypsin inhibitor heavy chain 5 (ITIH5) is overexpressed in inflammatory skin diseases and affects epidermal morphology in constitutive knockout mice and murine 3D skin models. Experimental Dermatology, März 2015 24, 663–668.

Dahl E, Jung A, Fassunke J, Hummel M, Penzel R, Dietmaier W, Laßmann S.
Chancen und Risiken der blutbasierten molekularpathologischen Analytik zirkulierender Tumorzellen (CTC) und zellfreier DNA (cfDNA) in der personalisierten Krebstherapie. Pathologe, Februar 2015 36, 92–97.

Rose M, Schubert C, Dierichs L, Gaisa N. T, Heer M, Heidenreich A, Knüchel-Clarke R, Dahl E.
OASIS/CREB3L1 is epigenetically silenced in human bladder cancer facilitating tumor cell spreading and migration in vitro. Epigenetics, Januar 2015 9(12), 1626 - 1640.

2014

Hummel M., Rufenach C.
Biomaterialbanken als Grundlage für die Entwicklung genetisch basierter Präventionskonzepte. Bundesgesundheitsblatt, Dezember 2014, DOI: https://doi.org/10.1007/s00103-014-2090-5.

Antony P, Rose M, Heidenreich A, Knüchel-Clarke R, Gaisa N. T, Dahl E.
Epigenetic Inactivation of ST6GAL1 in Human Bladder Cancer. BMC Cancer, Dezember 2014 14, 901.

Kloten V, Rose M, Kaspar S, von Stillfried S, Knüchel-Clarke R, Dahl E.
Epigenetic inactivation of the novel candidate tumor suppressor gene ITIH5 in colon cancer predicts unfavorable overall survival in the CpG island methylator phenotype. Epigenetics, August 2014 9(9), 1290 - 1301.

Huth L, Rose M, Kloubert V, Winkens W, Schlensog M, Hartmann A, Knüchel-Clarke R, Dahl E.
BDNF Is Associated with SFRP1 Expression in Luminal and Basal-Like Breast Cancer Cell Lines and Primary Breast Cancer Tissues: A Novel Role in Tumor Suppression? PLOS ONE July 2014 | Volume 9 | Issue 7 | e102558

Kahles F, Meyer C, Möllmann J, Diebold S, Findeisen H. M, Lebherz C, Trautwein C, Koch A, Tacke F, Marx N, Lehrke M.
GLP-1 Secretion Is Increased by Inflammatory Stimuli in an IL-6–Dependent Manner, Leading to Hyperinsulinemia and Blood Glucose Lowering. Diabetes, Oktober 2014 63, 3221–3229.

2013

Dahl E, Haller F.
Personalized urooncology based on molecular uropathology: what is the future? Urologe A. 2013 Jul;52(7):976-81. doi: 10.1007/s00120-013-3229-y. German.

Kloten V, Becker B, Winner K, Schrauder MG, Fasching PA, Anzeneder T, Veeck J, Hartmann A, Knüchel R, Dahl E.
Promoter hypermethylation of the tumor-suppressor genes ITIH5, DKK3, and RASSF1A as novel biomarkers for blood-based breast cancer screening. Breast Cancer Res. 2013 Jan 15;15(1):R4. doi: 10.1186/bcr3375.